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Cocaine research report
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Apply market research to generate audience insights. Measure content performance. Develop and improve products. List of Partners vendors. Cocaine is a highly addictive and illegal recreational drug that has a wide variety of well-understood effects on the body.
The drug produces euphoria, which is described as a feeling of pleasure and an extreme sense of invincibility, often leading to abuse of the drug and negative health consequences.
Effects of cocaine on body and brain
Cocaine users develop a tolerance over time and report that they are never able to achieve the "high" they felt the first time they used the drug. As tolerance to cocaine develops, most users say that the euphoric feeling they get with repeated use is not as intense or as long-lasting as it was with early use, even with escalating doses.
This often le to further physical and mental health problems. Cocaine is a strong central nervous system stimulant that affects the way the brain processes dopamine, a naturally produced neurotransmitter that is associated with regulating pleasure, movement, and other functions. Cocaine interferes with the brain's reabsorption removal of dopamine, prolonging dopamine's action, which produces a variety of effects.
Short-term and long-term effects of cocaine
Cocaine works almost immediately, but its effect ultimately le to a depletion of dopamine resulting in a "crash". Many users deal with this feeling by using more cocaine, which creates a cycle of use and withdrawal. Immediately after cocaine use, users will exhibit the following physical symptoms:. Shortly after using cocaine, the user experiences a euphoric periodwhich can last up to 30 minutes. Users typically feel:. Men and women who have used cocaine report feeling extremely depressed and agitated without the drug.
When the immediate euphoric rush of the cocaine wears off, the individual may experience a crash with the following effects on the body:. Many cocaine users also have unpleasant experiences along with the euphoria. These experiences can last anywhere from a couple of minutes to a few hours, depending on the dose and method by which the drug is taken.
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Repeated cocaine use can cause a variety of health effects on the body. These effects can happen right after using cocaine, or they can occur even after the drug wears off. Consequences of long-term cocaine use include:. Some of the long-term effects and symptoms associated with cocaine use are related to the dosage and method of use. Cocaine can be snorted, injected into the skin, or smoked. The method of cocaine use not only affects the length of the high, but it also comes with certain risks that further exacerbate long-term use symptoms.
When cocaine is injected, the euphoric feeling can last from 15 to 30 minutes. With chronic injections into the skin, cocaine can cause severe vasoconstriction constricted blood vessels that may prevent blood flowing into the tissue, resulting in severe tissue damage. The effect on the body can include severe allergic reactions, and increased risk for contracting HIV, hepatitis, heart infections, or sepsis a blood infection.
When cocaine is smoked, the high may last only five to 10 minutes. Risks include breathing difficulties, inflammation of the lungs, a chronic cough, and bronchitis.
When cocaine is snorted, it tends to reach the brain at a slower rate than smoking it and gives a milder euphoria, but it may last from 15 to 30 minutes. Health effects of snorting cocaine include a chronically runny nose, nosebleeds, loss of smell, hoarse voice, and problems swallowing. This condition is also referred to as "coke nose". When used in higher doses, cocaine can lead to overdose a condition where there is more of the substance in the body than the individual can cope with.
Injecting cocaine increases the risk of overdose, as users often do not know the strength or purity of the cocaine being used.
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Because cocaine affects the heart and respiratory system, an overdose can cause death, especially when you inject or smoke it. A total of 70, persons died from drug overdoses in the United States in ; approximately two-thirds of these deaths involved an opioid.
Among all drug overdose deaths, 13, Deaths from a combination of cocaine and opioids have more than doubled since While cocaine abuse is a well-known problem, the drug can result in such a strong addiction that users often continue to abuse it even after having suffered serious problems, such as seizures or heart attacks.
Often, recovering from drug addiction requires professional treatment, medical supervision, and methods of ability. For more mental health resources, see our National Helpline Database.
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Learn the best ways to manage stress and negativity in your life. In: StatPearls [Internet]. Updated October 21, National Institute on Drug Abuse. What is cocaine? Updated April What are the short-term effects of cocaine use? Updated May Side effects of cocaine abuse: multiorgan toxicity and pathological consequences. Curr Med Chem. Center for Substance Abuse Treatment. Treatment for Stimulant Use Disorders. Nasal Septum Perforation due to Cocaine Abuse.
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The High. The Crash. Short-Term Health Effects. Methods of Use. Effects of a Cocaine Overdose. Was this helpful? Thanks for your feedback! Up. What are your concerns? Article Sources.