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MDMA is a synthetic substance commonly known as ecstasyalthough the latter term has now been generalised to cover a wide range of other substances. Originally developed in by the Merck chemical company, it was never marketed as such. Although proposed as an aid to psychiatric counselling, therapeutic use is extremely limited.


MDMA, called "Adam," "ecstasy,", "e," or "X-TC" on the street, is a synthetic, psychoactive mind-altering drug with hallucinogenic and amphetamine-like properties.

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Its chemical structure methylenedioxy- methamphetamine is similar to two other synthetic drugs, MDA and methamphetamine, which are known to cause brain damage. MDMA is a so-called "deer drug," which, according to the Government and Drug Agencies, has become a nationwide problem as well as a serious health threat. It is known to be the cause of at least four deaths. Beliefs about ecstasy are reminiscent of similar claims made about LSD in the s and s, which proved to be untrue.

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According to its proponents, MDMA can make people trust each other and breaks down barriers between them. Many problems users encounter with MDMA are similar to those found with the use of amphetamines and cocaine.

Ecstasy (molecule of the month for january )

They are: psychological difficulties, including confusion, depression, sleep problems, drug craving, severe anxiety, and paranoia-during and sometimes weeks after taking MDMA even psychotic episodes have been reported ; physical symptoms such as muscle tension, involuntary teeth-clenching, nausea, blurred vision, rapid eye movements, faintness, and chills or sweating; increases in heart rate and blood pressure, a special risk for people with circulatory or heart disease.

NIDA has arranged to have MDMA synthesized so that qualified researchers can conduct studies on the drug's long-term neurotoxicity and abuse potential. Seiden and C. Schuster of the University of Chicago, MDA destroys serotonin-producing neurons, which play a direct role in regulating aggression, mood, sexual activity, sleep, and sensitivity to pain.

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It is probably this action on the serotonin system that gives MDA its purported properties of heightened sexual experience, tranquility, and conviviality. MDMA also is related in structure and effects to methamphetamine. Methamphetamine has been shown by the Chicago researchers to cause degeneration of neurons containing the neurotransmitter dopamine.

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Damage to these neurons is the underlying cause of the motor disturbances seen in Parkinson's disease. In laboratory experiments, a single exposure to methamphetamine at high doses or prolonged use at low doses destroys up to 50 percent of the brain cells that use dopamine.

Although this damage may not be immediately apparent, scientists believe that with aging or exposure to other toxic agents, Parkinsonian symptoms may eventually emerge. These symptoms begin with lack of coordination and tremors and may eventually result in a form of paralysis.

Methylenedioxymethamphetamine (mdma or 'ecstasy') drug profile

Treatment authorities in California reported at least three or four MDMA-related cases per month in Schedule I drugs are generally dangerous narcotics that have a high potential for abuse and no medical usefulness. The emergency scheduling was effective July 1, The scheduling will be effective for 1 year, during which time authorities will decide how best to classify MDMA in light of hearings and scientific research.

Until it became illegal, MDMA was used by some psychiatrists and therapists as an aid in psychotherapy.

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Underground chemists produce these new drugs by slightly changing the chemical composition of illegal drugs so that they are technically legal. In many cases, the new deer drugs are more dangerous and more potent than the original drug. High resolution images and illustrations are available on request.

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This attachment makes it also resemble the structure of the hallucinogen mescaline.


It is chemically similar to both stimulants and hallucinogens, producing feelings of increased energy, pleasure, emotional warmth, and distorted sensory and time perception.